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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Tdp-43 cryptic exons are highly variable between cell types

Fig. 2

Neuron-specific cryptic exons (CaMKIIα-Cre;Tardbp F/F knockout mice). (a) Visual examples of neuron-specific cryptic exons (Ap3b2, Camk1g). (b) Neuron-specific cryptic exons are flanked by UG repeats that are present upstream, downstream or within the cryptic exon sequence itself. (c to e) RT-PCR validation of cryptic exons (red arrows) in RNA extracted from hippocampi of 3 month old CaMKIIα-Cre;Tardbp F/F mice. Refer to Additional file 2 for a complete list of cryptic exons

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