Table 2 Fraction Aβ 1–20 formed during incubation of CSF at room temperature for 24 h, calculated based on the altered peptide isotope distribution due to the incorporation of H2 18O
From: Ex vivo 18O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway
Aβ1-20 | Aβ1-40 | |||
|---|---|---|---|---|
Patient # | Before treatment | After treatment | Before treatment | After treatment |
1 | 1.14 | ND | −0.03 | 0.05 |
2 | 1.10 | ND | 0.12 | −0.10 |
3 | 1.10 | ND | 0.16 | 0.04 |
4 | 0.59 | 0.15 | 0.18 | −0.16 |
5 | 1.02 | 0.27 | ND | 0.04 |
6 | 1.06 | 0.22 | −0.08 | 0.21 |