Skip to main content


Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

Fig. 1

MPTP injected C57BL/6 and humanized CD34+ mice showed reduced motor strength based on the grip strength and pole tests. The hCD34+ mice and age-matched C57BL/6 female mice were intraperitoneal injected three times with saline vehicle or MPTP-HCL (18 mg/kg) at 2 h intervals followed by FK506 injections (10 mg/kg/day) for 5 days. Mice were tested for grip strength (a, b) and pole test (c, d) 7 days post MPTP injections. Results were averaged from 8 to 10 mice (CD34+) and 4-10 (C57BL/6) per group and plotted ± SD (*p < 0.05)

Back to article page