Skip to main content
Fig. 9 | Molecular Neurodegeneration

Fig. 9

From: Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

Fig. 9

FK506 attenuated the MPTP-dependent increase of human inflammatory cytokine levels in humanized CD34+ mice serum. The hCD34+ mice were intraperitoneal injected three times with saline vehicle or MPTP-HCL (18 mg/kg) at 2 h intervals followed by FK506 injections (10 mg/kg/day) for 5 days. Eight days post MPTP injections, serum was collected and used for human specific multi-analyte cytokine ELISA arrays. Cytokine levels were determined from 6 animals per group ± SD (*p < 0.05)

Back to article page