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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination

Fig. 6

tPA expression after white matter damage in wild type mice. Photomicrographs from tissue sections show representative images of tPA (red), GFAP (green, first column), Iba1 (green, second column), CD31 (green, third column), Olig2 (green, fourth column) and DAPI staining (blue) immunoreactivities in the remyelinating corpus callosum of WT mice, 1, 3, 7, 14 and 21 days after lysolecithin injection. Asterisks show colocalization of tPA and CD31 immunoreactivities in endothelial cells. Filled arrowheads show colocalization of tPA and Olig2 immunoreactivities in oligogendrocytes. (Representative images, n = 3 per group). dpi: days post injection. Scale bars: 20 μm

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