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Table 4 Cerebral regions showing significant group differences between AD patients and controls across studies

From: Tau PET imaging: present and future directions

   CN
(n) 		AD
(n) 		Neocortex/Isocortical Hippocampus Parahippocampal gyrus Inferior temporal gyrus Superior temporal Lateral occipital lobe Posterior cingulate Parietal cortex Anterior cingulate Putamen/striatum
[18F]T807 Johnson et al., 2016 [59] 56 6   NS + +    +    
Cho et al., 2016 [57] 20 20 + + + + + a + + + NS
[18F]THK5117 Harada et al., 2015 [30] 8 8 + NS + + + NS + + NS NS
[18F]THK5317 data from Chiotis et al., 2016 [53] 9 9 + NS + + NS + + + NS NS
[18F]THK5351 Lockhart et al., 2016 [45] 6 10   NS NS +   a + + NS NS
  1. Only regions of interest that were comparable across studies are listed in this table
  2. + indicates that a significant difference between groups was reported; grey empty cells correspond to cerebral regions that were not reported in the publication
  3. a: a significant difference was found when the whole occipital cortex was assessed. AD Alzheimer’s disease, CN cognitively normal, NS not significant
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Molecular Neurodegeneration

ISSN: 1750-1326