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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Quantitative proteomic analysis of Parkin substrates in Drosophila neurons

Fig. 3

Characteristics of the data set. a Three independent BioUb pulldowns were performed for each condition generating 1522 protein identifications by mass spectrometry of which 1132 were considered to be ubiquitinated by imposing a threshold of four-fold change in LFQ intensity relative to BirA control. b Venn diagram shows the overlap between proteins identified as ubiquitinated under different conditions, indicating that Parkin expression does not dramatically alter the global ubiquitome

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