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Fig. 9 | Molecular Neurodegeneration

Fig. 9

From: Quantitative proteomic analysis of Parkin substrates in Drosophila neurons

Fig. 9

Functional connectivity of the most robust Parkin responders identified in Drosophila neurons. Cellular compartment representation of 35 enriched (green) and 2 reduced (red) human homolog proteins in purified ubiquitinated material from ParkinWT over-expressing Drosophila neurons (Table 1). STRING (http://string-db.org/) analysis based on experimental data shows the connectivity. Strength of dotted lines represents differential significance (darker lines show higher significance). Yellow circles indicate ParkinWT dependent ubiquitination sites identified in Drosophila proteins

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