Fig. 1
From: Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model
DcR3 improved the hippocampus-related cognitive deficits in APP mice. Mice were subjected to a-c the Morris water maze test and d-f the fear conditioning test. a The mean daily escape latencies calculated from six trials per day in the hidden platform test. b The number of times that the mice crossed the original platform location in the probe trial. c Swimming speed during probe trials. d Freezing behavior during training day of fear conditioning test. e, f Percent of time freezing in the e contextual test and f cued test on the second day. g Distance moved in the open field test during 15 min. h Distance traveled in the open or closed arms of the elevated plus test during 10 min. N = 5-11 mice per genotype. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001