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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model

Fig. 6

Downregulating ANP32A decreases formation of INHAT complex. a The association level between ANP32A and histone 3 (H3) increased in hippocampal CA3 of htau mice, while siANP32A reduced the interaction detected by co-immunoprecipitation using antibodies as indicated on the blots. b The association level between ANP32A and histone 4 (H4) increased in hippocampal CA3 of htau mice, while siANP32A reduced the interaction detected by co-immunoprecipitation. c The association levels between SET and H3 or H4 or ANP32A increased in hippocampal CA3 of htau mice, while siANP32A reduced the interaction detected by co-immunoprecipitation

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