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Table 1 AD-risk loci identified through genome-wide analyses (GWAS and GWAX) [24, 25]

From: Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

SNP Chr Reported gene Additional genes in locus
rs6656401 1 CR1  
rs6733839 2 BIN1  
rs35349669 2 INPP5D NGEF, NEU2
rs190982 5 MEF2C LOC645323, MIR9-2
rs2074612a 5 SCIMP ZNF594, RABEP1, USP6
rs9271192 6 HLA-DRB5– HLA-DRB1 C6orf10, HLA-DRB5, HLA-DRB6, HLA-DRB1, HLA-DQA1, HCG23, BTNL2, HLA-DRA, HLA-DQB1, HLA-DQA2, HLA-DQB2, HLA-DOB, TAP1, TAP2, PSMB8, PSMB9
rs10948363 6 CD2AP GPR111, GPR115
rs2718058 7 NME8 GPR141
rs1476679 7 ZCWPW1 TRIM4, GJC3, AZGP1, AZGP1P1, ZKSCAN1, ZSCAN21, ZNF3, COPS6, MCM7, C7orf59, GPC2, STAG3, GATS, PVRIG, SPDYE3, PMS2P1, PILRA, PILRB, PPP1R35, MEPCE, NYAP1, SAP25, AGFG2, LRCH4, ZASP, LRCH4, FBXO24, PCOLCE-AS1
rs11771145 7 EPHA1 CLCN1, FAM131B, ZYX, TAS2R60, LOC285965, TAS2R41
rs28834970 8 PTK2B STMN4, TRIM35, CHRNA2, EPHX2
rs9331896 8 CLU PTK2B, CHRNA2, EPHX2, SCARA3, CCDC25, ESCO2, PBK
rs7920721a 10 ECHDC3  
rs10838725 11 CELF1 ARFGAP2, PACSIN3, DDB2, ACP2, MADD, MYBPC3, SPI1, SLC39A13, PSMC3, RAPSN, PTPMT1, KBTBD4, NDUFS3, C1QTNF4, MTCH2, AGBL2, FNBP4, NUP160
rs983392 11 MS4A6A PLAC1L, MS4A3, MS4A2, MS4A4A, MS4A6E
rs10792832 11 PICALM CCDC83
rs11218343 11 SORL1  
rs17125944 14 FERMT2 ERO1L, PSMC6, STYX, GNPNAT1
rs10498633 14 SLC24A4 RIN3
rs59685680a 15 SPPL2A TRPM7, USP50
rs77493189a 17 HBEGF HBEGF
rs4147929 19 ABCA7 CFD, MED16, PRTN3, R3HDM4, KISS1R, ELANE, ARID3A, TMEM259, GRIN3B, WDR18, HMHA1, CNN2, POLR2E, SBNO2, GPX4, ATP5D, MIDN, CIRBP, EFNA2
rs7274581 20 CASS4 CSTF1, RTFDC1, GCNT7, FAM209A, FAM209B
  1. Disease-associated SNPs that have reached genome-wide significance for each locus are labeled, along with their chromosome, the closest gene (that which is reported) and additional genes within the locus
  2. aidentified in GWAX