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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategies

Fig. 3

Specificity of anti-alpha-synuclein NAb binding. The ability of increasing concentrations of a α-synuclein monomer or b amyloidβ1–40 (Aβ1–40) to inhibit the binding of α-synuclein NAbs to α-synuclein coated ELISA plates. Data are presented as % inhibition (PI) relative to the unblocked condition. Pooled plasma samples are from 10 Parkinson’s Disease (PD-blue, squares), 10 Multiple System Atrophy (MSA-green, triangles) patients and 10 normal controls (NC-black, circles) were diluted 1:400. The lines in a represents the fitting of a one site model to the data

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