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Table 2 Characteristics of patients with DS of the cohort 2

From: Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and down syndrome

Case

Sex

Age (years)

Social Agea (years), BL

ΔSocial Ageb (years)

Mean cortical SUVR (PiB-PET)

Plasma p-tau181 (pg/ml)

1

M

36

8.75

1.10

1.553

0.0000

2

F

26

4.17

N/A

N/A

0.0000

3

F

19

4.50

2.00

1.400

0.0000

4

M

26

4.92

0.19

1.536

0.0000

5

F

22

7.42

−0.10

1.142

0.0000

6

F

31

N/A

N/A

N/A

0.0000

7

F

24

10.0

N/A

N/A

0.1494

8

F

25

7.00

N/A

N/A

0.0000

9

M

48

4.42

N/A

N/A

0.2040

10

M

25

7.08

−1.00

1.578

0.1408

11

F

45

1.92

N/A

N/A

2.0731

12

M

26

6.50

−1.10

N/A

0.2787

13

M

57

4.08

N/A

N/A

1.3516

14

M

31

2.33

N/A

N/A

0.2382

15

F

55

2.42

N/A

1.828

4.0296

16

F

42

4.17

N/A

N/A

2.7619

17

M

43

6.08

N/A

N/A

3.3685

18

M

25

N/A

N/A

N/A

0.3256

19

M

29

4.67

N/A

N/A

0.4112

20

F

45

8.33

N/A

N/A

0.0000

  1. BL Baseline, SUVR standardized uptake value ratio, N/A not available
  2. aSocial ages were estimated using social maturity scale revised (S-M). Although data were calculated as units of years and months on this buttery [18], we recalculated those into unit of years for statistical analysis. Social ages in this figure were represented as unit of years
  3. b“ΔSocial Age” represents the changes of the social age in individual DS patients who can be evaluated twice, approximately 1 year apart
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Molecular Neurodegeneration

ISSN: 1750-1326