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Table 1 Baseline characteristics of the study participants

From: Whole blood gene expression and white matter Hyperintensities

Characteristics

Offspring cohort (n = 1397)

Third generation cohort (n = 1851)

Women, n (%)

757 (54.2%)

1000 (54.0%)

Age, years (mean ± SD)

66.4 ± 9.0

48.0 ± 8.5

WMH, median (25th, 75th percentile)

2.41 (1.25, 4.69)

1.28 (0.92, 1.75)

Ln(WMH + 1), median (25th, 75th percentile)

1.23 (0.81, 1.74)

0.82 (0.65, 1.01)

Total cranial volume, median (25th, 75th percentile)

1222 (1143, 1307)

1254 (1170, 1344)

Current smoker, n (%)

97 (6.9%)

174 (9.4%)

Hypertension, n (%)

828 (59.3%)

135 (7.3%)

Body mass index (BMI), median (25th, 75th percentile)

27.52 (24.52, 30.78)

27.11 (23.98, 30.72)

Total cholesterol, median (25th, 75th percentile)

185 (162, 210)

184 (163, 207)

HDL, median (25th, 75th percentile)

56 (45, 68)

57 (47, 71)