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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Fig. 3

Higher extracellular acidification rates in sALS and PLS fibroblasts. Scatter plots of ECAR baseline a Control mean: 2035.9, SD: 987.4; sALS mean: 2536.0, SD: 1237.8; PLS mean: 3909.1, SD: 2175.4; C9Orf72 mean: 3381.9, SD: 2988.0), ECAR AA-Rot b Control mean: 2631.1, SD: 1164.4; sALS mean: 3126.2, SD: 1366.6; PLS mean: 4895.2, SD: 2661.5; C9Orf72 mean: 3426.1, SD: 2425.9), and OCR base/ECAR base c Control mean: 1.5, SD: 0.8; sALS mean: 1.4, SD: 0.7; PLS mean: 1.2, SD: 0.6; C9Orf72 mean: 1.8, SD: 1.7) values are shown comparing sALS, PLS, C9Orf72, and control lines. The method by which features were calculated is illustrated in Fig. 2a. Middle bars represent the average values and error bars show standard deviations. p-values are indicated where there was a significant difference between two groups. n.s.: no significant difference. n = 171 sALS; n = 34 PLS, n = 13 C9Orf72, n = 91 controls

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