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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

Fig. 4

Expression profile clustering identifies alterations associated with bioenergetic control. Nodes (spheres) represent individual proteins and edges (lines) reflect the strength of correlation of expression between proteins. The schematic displays 2 distinct protein networks – proteins displaying increased abundance in synaptic mitochondria on the left and those exhibiting enhanced expression in non-synaptic mitochondria on the right. Coloured nodes represent protein clusters based on expression profile and each cluster displays their representative functions determined by DAVID. Graph clustered by Pearson r = 0.98

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