Fig. 4
From: NADPH oxidases in Parkinson’s disease: a systematic review
Proposed role for NADPH oxidases in PD. Schematic view of the link between both microglial and neuronal NADPH oxidases and cellular processes related to PD, e.g. alpha-synuclein signaling, microglia activation, oxidative stress and neuronal damage, mitochondria dysfunction, disruption of the autophagy-lysosome system, synaptic dysfunction and excitotoxicity. Localizations of NADPH oxidases are indicated in grey