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Table 1 Human NADPH oxidases genes, genomic positions and isoforms

From: NADPH oxidases in Parkinson’s disease: a systematic review

NADPH oxidase catalytic subunit Official Gene symbol and Full Name HUGOa Other Proposed Aliasesb Entrez Gene IDdb Genomic locationb mRNA (RefSeq Accession Numbers; GRCh38/hg38 human genome)c
Nox1 NOX1 NADPH oxidase 1 MOX1; NOH1; NOH-1; GP91-2 27035 Xq22.1 NM_007052 (isoform 1)
NM_013955 (isoform 2)
NM_001271815 (isoform 3)
Nox2 CYBB cytochrome b-245 beta chain CGD; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX 1536 Xp21.1-p11.4 NM_000397 → NP_000388
Nox3 NOX3 NADPH oxidase 3 het; GP91-3; nmf250 50508 6q25.3 NM_015718 → NP_056533
Nox4 NOX4 NADPH oxidase 4 KOX; KOX-1; RENOX 50507 11q14.3 NM_016931 (isoform a)
NM_001143836 (isoform b)
NM_001143837 (isoform c)
NM_001291926 (isoform d)
NM_001291927 (isoform e)
NM_001291929 (isoform f)
NM_001300995 (isoform g)
Nox5 NOX5 NADPH oxidase 5 NOX5A, NOX5B 79400 15q23 NM_024505 (isoform 1)
NM_001184779 (isoform 2)
NM_001184780 (isoform 3)
Duox1 DUOX1 dual oxidase 1 LNOX1; THOX1; NOXEF1 53905 15q21.1 NM_017434 (dual oxidase 1 precursor)
NM_175940 (dual oxidase 1 precursor)
Duox2 DUOX2 dual oxidase 2 TDH6; LNOX2; THOX2; NOXEF2; P138-TOX 50506 15q21.1 NM_001190392 dual oxidase 2 precursor
NM_177610 dual oxidase 2 precursor
NM_213999 dual oxidase 2 precursor
NM_024141 dual oxidase 2 precursor
  1. aHUGO: Accessed January 5 2017
  2. bNCBI Entrez Gene: Accessed January 5 2017
  3. chuman GRCh38/hg38 genome: Accessed January 5 2017