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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: A validated antibody panel for the characterization of tau post-translational modifications

Fig. 1

Scheme of tau (2N4R) with PTM sites that are covered by commercially available antibodies. Phosphorylated residues are labeled in red, other modifications in black. N1 and N2: N-terminal inserts 1 and 2, respectively. R1, R2, R3, and R4: Repeat domains 1–4. pY: phospho-tyrosine, pT: phospho-threonine, pS: phospho-serine, nY: nitrated tyrosine, acK: acetylated lysine, meK: dimethylated lysine, C3-D: caspase-3 cleaved aspartic acid

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