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Fig. 10 | Molecular Neurodegeneration

Fig. 10

From: A validated antibody panel for the characterization of tau post-translational modifications

Fig. 10

A panel of validated antibodies detects the subcellular distribution of tau in hiPSC-derived neurons. The panel of pan-tau (a - f, Tau1, Tau5, Tau12, HT7, BT2, and Dako) and isoform-specific (g - j 0 N, 2 N, 3R and 4R) tau antibodies were tested by immunofluorescence by using hiPSC-derived neurons. While no signal was observed for Tau5 (b), 3R (i) and 4R (j) antibodies, all other stainings detect tau in both cell bodies and neurites. Green: antibody staining, blue: Hoechst staining. Scale bars represent 100 μm

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