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Fig. 11 | Molecular Neurodegeneration

Fig. 11

From: A validated antibody panel for the characterization of tau post-translational modifications

Fig. 11

Non-phospho PTMs are present in hiPSC-derived neurons. nY18 (a) and meK311 (d) antibody staining reveals the presence of nitrated and dimethylated tau in both the cell bodies and neurites of hiPSC-derived neurons. acK280 staining shows nuclear localization (c), while no signal was obtained for the nY29 (b) and C3-D421 (e) modifications. Green: antibody staining, blue: Hoechst staining. Scale bars represent 100 μm

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