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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: A validated antibody panel for the characterization of tau post-translational modifications

Fig. 2

Peptide arrays validate the specificity of antibodies detecting non-phospho-PTMs on tau. a nY18, b nY29, c acK280 and d meK311 antibodies demonstrated specific detection of the respective modifications on a peptide array. While all antibodies are specific, the detection of acK280 (c) and meK311 (d) depends on the surrounding peptide sequence. The sequence and modification profile for peptides immobilized in each spot are shown below the blots. The modification targeted by the antibody is shown in bold red, off-target modifications are shown in bold black

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