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Fig. 9 | Molecular Neurodegeneration

Fig. 9

From: Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice

Fig. 9

P150Glued and other dynactin subunits are present in the postsynaptic sites. Subcellular fractionation of 3-month-old wild-type mouse brains shows the distribution of dyanctin subunits p150Glued, p135+, p50 and ARP1, dynein subunits DHC, DIC and DLC, synaptophysin (SYP), postsynaptic density protein 95 (PSD95), and α-tubulin in total brain lysates (Total), crude nuclear fraction (P1’), cytosol (Cyt), light membrane fraction (LM), synaptosomes (Syn), and postsynaptic density (PSD)

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Molecular Neurodegeneration

ISSN: 1750-1326