Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells

Table 1 Cognitive-related genes analysed in the study, divided into the metabolic processes they are involved in

Process	Gene symbol	Gene name
Amyloid peptide metabolism	App	Amyloid precursor protein
	Naat16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit
	Sorl1	Sortilin related receptor 1
	Tmcc2	Transmembrane and coiled-coil domain family 2
Neuronal viability/function	Bdnf	Brain derived neurotrophic factor
	Casp3	Caspase 3
	Fndc5	Fibronectin type III domain containing 5
Transcription factor-mediated regulation of cognitive-related processes	Creb	cAMP responsive element binding protein 1
	Nrf2	NF-E2-related factor 2
	Pgc1α	PPARG coactivator 1 alpha
	Zpr1	Zinc finger protein 259
Synaptic function/signalling	Syn1	Synapsin I
Synaptic function/signalling	Trkb	Neurotrophic receptor tyrosine kinase 2
Inflammation	Tnf α	Tumour necrosis factor α

ISSN: 1750-1326