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Table 3 Correlations between gene expression in the hippocampus and HOMA-IR at the age of 6 months

From: Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells

 

HF45

HF60

Genes

R

p value

R

p value

App

0.036

0.895

0.595*

0.032

Bdnf

−0.536*

0.027

−0.429

0.111

Casp3

−0.181

0.486

0.080

0.786

Creb

0.066

0.800

−0.248

0.372

Fdnc5

−0.403

0.137

0.337

0.260

Naat16

−0.507*

0.038

−0.622*

0.013

Nrf2

0.292

0.273

−0.172

0.541

Pgc1α

−0.207

0.460

0.383

0.196

Sorl1

−0.169

0.516

−0.489

0.064

Syn1

−0.312

0.223

−0.516*

0.049

Tmcc2

−0.535*

0.027

−0.738**

0.002

Tnfα

−0.159

0.604

0.561

0.091

Trkb

0.329

0.214

−0.769**

0.001

Zpr1

−0.533*

0.033

−0.693**

0.006

  1. R Pearson correlation coefficients; boldface indicates statistical significance; *p < 0.05; **p < 0.01