TY - JOUR AU - Rangaraju, Srikant AU - Dammer, Eric B. AU - Raza, Syed Ali AU - Rathakrishnan, Priyadharshini AU - Xiao, Hailian AU - Gao, Tianwen AU - Duong, Duc M. AU - Pennington, Michael W. AU - Lah, James J. AU - Seyfried, Nicholas T. AU - Levey, Allan I. PY - 2018 DA - 2018/05/21 TI - Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease JO - Molecular Neurodegeneration SP - 24 VL - 13 IS - 1 AB - Disease-associated-microglia (DAM) represent transcriptionally-distinct and neurodegeneration-specific microglial profiles with unclear significance in Alzheimer’s disease (AD). An understanding of heterogeneity within DAM and their key regulators may guide pre-clinical experimentation and drug discovery. SN - 1750-1326 UR - https://doi.org/10.1186/s13024-018-0254-8 DO - 10.1186/s13024-018-0254-8 ID - Rangaraju2018 ER -