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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

Fig. 5

qPCR validation of differential expression of striatal genes in YAC128 mice. Shown are RNAseq and qPCR results for genes differentially expressed in the striatum of YAC128 mice after pridopidine treatment. “**” and “##” represent significant (Adj. p-val < 0.05) differential expression in YAC128 Veh-WT Veh and YAC128 Low/High-YAC128 Veh contrasts, respectively. “High” = 30 mg/kg of pridopidine; “Low” = 10 mg/kg of pridopidine; “Veh” = vehicle

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Molecular Neurodegeneration

ISSN: 1750-1326