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Table 1 Nomenclature and descriptions of iPSC lines used in this study

From: iPSC-derived familial Alzheimer’s PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling

Line

Sex

APOE

Genotype

Reprogramming Method

Control

Male

E3/E3

Normal

Sendai virus

fControl

Female

E3/E3

Normal

mRNA Transfection

AD1

Female

E3/E4

PSEN2 N141I

mRNA Transfection

AD2

Female

E3/E3

PSEN2 N141I

mRNA Transfection

iAD1

Female

E3/E4

Normal (Corrected AD1)

mRNA Transfection

iAD2

Female

E3/E3

Normal (Corrected AD2)

mRNA Transfection