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Table 2 Top 10 enriched GO terms from differentially expressed genes in TCX

From: TMEM106B haplotypes have distinct gene expression patterns in aged brain

GO Process

P value

FDR

# Genes

single organism signaling

1.801E-20

5.424E-17

253

signaling

1.986E-20

5.424E-17

253

cell communication

5.539E-20

1.008E-16

256

G-protein coupled receptor signaling pathway

3.527E-19

2.908E-16

74

chemical synaptic transmission

4.260E-19

2.908E-16

59

trans-synaptic signaling

4.260E-19

2.908E-16

59

synaptic signaling

4.260E-19

2.908E-16

59

anterograde trans-synaptic signaling

4.260E-19

2.908E-16

59

multicellular organismal process

3.899E-18

2.366E-15

297

cell-cell signaling

3.492E-17

1.907E-14

91

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Molecular Neurodegeneration

ISSN: 1750-1326