Table 4 Modules significantly correlated to the TMEM106B rs3173615 status in TCX
From: TMEM106B haplotypes have distinct gene expression patterns in aged brain
Module | Correlation | P value | Top GO | FDR | Hub gene |
|---|---|---|---|---|---|
turquoise | 0.35 | 2e-04 | synaptic transmission | 6.64E-37 | FGF14 |
greenyellow | 0.27 | 0.004 | Ribonucleoprotein complex biogenesis | 1 | OXR1 |
darkgrey | 0.24 | 0.01 | centriolar satellite | 1 | IGSF9B |
midnightblue | 0.24 | 0.01 | ribosome binding | 0.99 | TRAPPC2L |
brown | −0.37 | 7e-05 | cell-cell adhesion | 6.24E-07 | PDLIM5 |
tan | −0.25 | 0.009 | cellular response to zinc ion | 0.025 | MFSD6 |
black | −0.23 | 0.01 | vasculature development | 2.01E-19 | ADGRL4 |
darkred | −0.22 | 0.02 | humoral immune response | 0.0002 | LIMK2 |
lightgreen | −0.21 | 0.03 | cytosolic ribosome | 2.98E-123 | RPS19 |
lightyellow | −0.2 | 0.04 | extracellular matrix organization | 9.04E-14 | DSP |