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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain

Fig. 3

Analysis of GRS vs. microglial densities across four regions for each measured stage of activation. Two-sided uncorrected P-values derived from robust regression are shown within tiles. Models co-varied for age at death, sex, and three EIGENSTRAT principal components. The color scale indicates magnitude and direction of the effect T-statistic. *significant after FDR correction (PFDR < 0.05)

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