Fig. 4
From: Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain
Analysis of individual variants in the RA GRS on microglial density in the ventral medial caudate. Published effect sizes on the x-axis have been transformed using a natural logarithm and oriented in the positive direction to align allelic effects (color denotes direction of effect on microglial density). P-values (uncorrected) are two-sided and derived from robust iterated re-weighted least squares regression models, co-varying for age at death, sex, and three EIGENSTRAT principal components