Table 4 Genes downregulated in Nrf1f/f; Six3-Cre that are enriched in Atoh7+ cells
From: Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis
| Â | Gene name | FC | Spatial expression |
|---|---|---|---|
Transcription factor | Barhl2 | −1.63 | RGC |
Ebf1 | −2.63 | RGC | |
Ebf3 | −3.09 | RGC | |
Irx2 | − 2.35 | RGC | |
Irx3 | −1.97 | RGC | |
Irx5 | −2.43 | RGC | |
Irx6 | −2.18 | RGC | |
Isl1 | −2.43 | RGC | |
Myt1 | −2.14 | RGC | |
Onecut3 | −2.15 | RGC | |
Pou4f1 | −2.62 | RGC | |
Pou4f2 | −1.89 | RGC | |
Pou6f2 | −2.28 | RGC | |
Ptf1a | −2.02 | retina | |
Tub | −2.38 | RGC | |
Neuron differentiation | Actl6b | −2.2 | RGC |
Adcyap1 | −1.71 | RGC | |
Bsn | −2.27 | RGC | |
Celsr3 | −2.35 | RGC | |
Cend1 | −1.89 | RGC | |
Cntn2 | −3.09 | RGC | |
Dcx | −2.87 | RGC | |
Dner | −2.08 | RGC | |
Dnm3 | −1.7 | unknown | |
Dok5 | −1.52 | retina | |
Dscam | −2.5 | retina | |
Elavl3 | −1.52 | RGC | |
Elavl4 | −2.67 | retina | |
Gap43 | −3.02 | RGC | |
Gprin1 | −2.51 | retina | |
Ina | −3.56 | RGC | |
Insc | −1.88 | unknown | |
Islr2 | −3.49 | RGC | |
Kif5a | −2.66 | RGC | |
Klhl1 | −1.76 | RGC | |
L1cam | −2.65 | RGC | |
Mapt | −4.37 | RGC | |
Mmp24 | −2.32 | RGC | |
Myo16 | −1.61 | RGC | |
Myt1l | −2.61 | RGC | |
Nefl | −3.67 | RGC | |
Nefm | −2.46 | RGC | |
Nell2 | −3.49 | RGC | |
Nptx1 | −1.63 | RGC | |
Nrn1 | −2.91 | RGC | |
Ret | −3.75 | RGC | |
Scn3b | −2.77 | RGC | |
Scrt1 | −2.11 | RGC | |
Sez6l | −2.56 | RGC | |
Slit1 | −1.81 | RGC | |
Snap25 | −2.41 | RGC | |
Stmn2 | −3.26 | RGC | |
Stmn3 | −3.65 | RGC | |
Th | −2.45 | retina | |
Tnik | −1.63 | unknown | |
Tubb3 | −2.38 | RGC | |
Unc13a | −2.62 | RGC | |
Others | 1810041L15Rik | −2.49 | RGC |
A930011O12Rik | −2.08 | unknown | |
Ajap1 | −1.66 | RGC | |
Akap6 | −3.68 | RGC | |
Apba2 | −1.93 | RGC | |
Arg1 | −1.55 | RGC | |
Atp1a3 | − 1.7 | retina | |
Cacna1b | −2.28 | RGC | |
Calb2 | −2.96 | RGC | |
Ccnd1 | −1.83 | RPC | |
Cda | −1.56 | RGC | |
Celf3 | −2.19 | RGC | |
Celf5 | −1.89 | retina | |
Chga | −1.65 | RGC | |
Chgb | −1.72 | RGC | |
Chst8 | −1.95 | RGC | |
Coro2a | −1.85 | RGC | |
Crmp1 | −2.78 | RGC | |
D930028M14Rik | −1.8 | RGC | |
Disp2 | −2.82 | RGC | |
Dnajc6 | −1.78 | RGC | |
Dusp26 | −2.37 | RGC | |
Eya2 | −1.59 | RGC | |
Fam155a | −1.76 | RGC | |
Fam78b | −1.73 | unknown | |
Fgf15 | −1.61 | RPC | |
Gabbr2 | −1.97 | unknown | |
Gdap1l1 | −1.91 | RGC | |
Grm2 | −2.67 | unknown | |
Hecw1 | −2.5 | RGC | |
Hspa12a | −2.21 | retina adult | |
Igfbpl1 | −2.25 | RGC | |
Iqsec3 | −1.53 | RGC | |
Kcnq2 | −2.47 | unknown | |
Mapk11 | −1.75 | RGC | |
Mtus2 | −2.7 | RGC | |
Nacad | −2.65 | RGC | |
Nhlh2 | −2.68 | RGC | |
Nmnat2 | −2.43 | RGC | |
Nsg2 | −3.26 | RGC | |
Pak7 | −2.04 | unknown | |
Ppp2r2b | −1.8 | RGC | |
Ppp2r2c | −1.88 | unknown | |
Rab3c | −2.12 | RGC | |
Rph3a | −2.58 | RGC | |
Rtn1 | −2.59 | RGC | |
Rundc3a | −2.27 | RGC | |
Rusc1 | −1.92 | RGC | |
Scg3 | −2.94 | RGC | |
Scn3a | −2.4 | unknown | |
Sez6l2 | −2.56 | RGC | |
Slc17a6 | −2.88 | RGC | |
Smpd3 | −1.97 | RGC | |
Sncg | −4.74 | RGC | |
Spire2 | −1.54 | RGC | |
Srrm3 | −2 | unknown | |
Sst | −2.14 | RGC | |
Stk32a | −1.83 | RGC | |
Svop | −2.17 | RGC | |
Thsd7b | −2.45 | unknown | |
Trim46 | −1.56 | unknown | |
Trp53i11 | −1.79 | RGC | |
Tubb2a | −2.35 | unknown | |
Unc79 | −2.31 | unknown | |
Vwa5b2 | −1.67 | RGC | |
Xkr7 | −1.69 | unknown |