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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Fig. 5

Clusters of the DEGs in rTg4510 microglia. The total 4672 DEGs in rTg4510 were classified into four major clusters using hierarchical clustering based on the correlations of expression profiles. In each plot, X axis represents the age (month) and y axis represents the normalized gene expression value (log2 converted). Each plot represents the overall expression profile of the genes in one cluster. The dots are the median expression values of genes in each replicates within the cluster, while the line indicates the median expression values of genes in the cluster. Lines representing WT are in red, whereas lines for transgenic are in green. The enriched KEGG pathways are listed besides each cluster

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Molecular Neurodegeneration

ISSN: 1750-1326