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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

Fig. 5

Glucose metabolism in different types of microglial cells. BV2 and B6M7 cells were untreated (control), or treated with LPS + IFNγ or IL-4 for 24 h. a, d Representative ECAR profiles of BV2 (a) and B6M7 (d) cells following glucose, oligomycin and 2-DG treatments in the Glycolysis Stress assay. b, e Changes in basal ECAR in LPS + IFNγ treated and IL-4 treated microglial cells compared to naïve microglia. c, f Changes in glycolytic capacity in LPS + IFNγ treated and IL-4 treated cells compared to naïve microglia. Mean ± SEM, n = 3 repeated experiments, **P < 0.01, ***P < 0.001

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