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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Fig. 4

Cortical pTDP-43 (pS409/410) pathology detected in (G4C2)149–mice. a-f Representative images of immunohistochemical analysis of pTDP-43 in the cortex of (G4C2)2 (a-c) and (G4C2)149 mice (d-f) at 3, 6, and 12 months of age. g Quantitative analysis of pTDP-43 inclusions in the cortex. Data represent the mean ± SEM. ****p < 0.0001 as analyzed by 1-way ANOVA followed by Tukey’s post-hoc analysis. Scale bar represents 20 μm

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