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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

Fig. 3

Pacer and Rubicon localization in the spinal cord of symptomatic SOD1G93A transgenic mice. Confocal microscopy of lumbar spinal cord sections of late symptomatic (138 to 156 days old) SOD1G93A transgenic mice (SOD1G93A-Tg) compared to age-matched non-transgenic controls (non-Tg). Z-stack of confocal images, detection of Pacer, the neuronal marker NeuN in a, or the astrocytic marker GFAP in b, detection of Rubicon, the neuronal marker NeuN in c, or the astrocytic marker GFAP in d. a-d, Nuclei are stained with DAPI. Scale bar: 20 μm

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