Table 1 Demographic Characteristics of study participants
From: TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers
|  | Controls | Alzheimer’s Disease Sporadic (Cases) | TREM2-carriers |
|---|---|---|---|
Knight-ADRC | |||
 No. of patients | 12 | 24 | 15 |
 Gender (% male) | 33.3 | 45.8 | 53.3 |
 Mean age at death (SD), years | 90.1 (8.9) | 85.1 (8.6) | 84.5 (6.3) |
 Mean RIN (SD) | 6.7 (1.2) | 5.9 (1.4)) | 6.8 (1.3) |
 APOE genotype (ε4+)% | 8.3 | 45.8 | 53.3 |
Mount Sinai Brain Bank (MSBB-BM36) | |||
 No. of patients | 28 | 93 | 11 |
 Gender (% male) | 50 | 32.3 | 45.5 |
 Mean age at death (SD), years | 80.9 (9.1) | 84.4 (7.2) | 84.3 (4.6) |
 Mean RIN (SD) | 6.6 (1.1) | 5.9 (1.5) | 6.0 (1.7) |
 APOE genotype (ε4+)% | 11.8 | 60 | 50 |
Mayo Clinic Brain Bank (MCBB) | |||
 No. of patients | 78 | 77 | 7 |
 Gender (% male) | 51.3 | 42.9 | 14.3 |
 Mean age at death (SD), years | 82.5 (8.9) | 82.3 (7.8) | 81.6 (4.6) |
 Mean RIN (SD) | 7.6 (1.0) | 8.6 (0.6) | 8.3 (0.3) |
 APOE genotype (ε4+)% | 10.3 | 51.9 | 57.1 |