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Table 1 Demographic Characteristics of study participants

From: TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

  Controls Alzheimer’s Disease Sporadic (Cases) TREM2-carriers
Knight-ADRC
 No. of patients 12 24 15
 Gender (% male) 33.3 45.8 53.3
 Mean age at death (SD), years 90.1 (8.9) 85.1 (8.6) 84.5 (6.3)
 Mean RIN (SD) 6.7 (1.2) 5.9 (1.4)) 6.8 (1.3)
 APOE genotype (ε4+)% 8.3 45.8 53.3
Mount Sinai Brain Bank (MSBB-BM36)
 No. of patients 28 93 11
 Gender (% male) 50 32.3 45.5
 Mean age at death (SD), years 80.9 (9.1) 84.4 (7.2) 84.3 (4.6)
 Mean RIN (SD) 6.6 (1.1) 5.9 (1.5) 6.0 (1.7)
 APOE genotype (ε4+)% 11.8 60 50
Mayo Clinic Brain Bank (MCBB)
 No. of patients 78 77 7
 Gender (% male) 51.3 42.9 14.3
 Mean age at death (SD), years 82.5 (8.9) 82.3 (7.8) 81.6 (4.6)
 Mean RIN (SD) 7.6 (1.0) 8.6 (0.6) 8.3 (0.3)
 APOE genotype (ε4+)% 10.3 51.9 57.1