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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

Fig. 3

NSC-exo and MN-exo injected ICV diffuse in the brain parenchyma and are taken up by neuronal cells. Exosomes prepared from the conditioned medium of NSC (NSC-exo) and NSC-derived mature neurons (MN-exo) were labeled with PKH-26 and injected ICV in adult mice four hours before euthanasia. Representative confocal images of mouse brain cross sections showing numerous labeled exosomes (shown in red) in neuronal cells (identified by NeuN immunofluorescence: shown in blue) in the cortex and hippocampus. Images are representative of 3 independent experiments. Calibration bar = 50 μm

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