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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

Fig. 6

NSC-exo, but not MN-exo, reduce hippocampal synaptic vulnerability to Aβo binding. Fresh hippocampal brain slices were prepared from male wt mice and treated with NSC-exo or MN-exo for 4 h before being challenged with Aβ oligomers (2.5 μM for 30 min). Synaptosomes were then isolated from each brain slice and the amount of bound Aβ measured using a specific ELISA. N = 3 mice/group, 3 slices/mouse. *p < 0.05; Student’s two-tailed T-test

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