Table 2 Clinical Diagnoses of 227 Patients with a Pathologic Diagnosis of Pure AD. More than a third of pathologic AD cases on the Mayo Clinic Brain Bank from 2007 to 2016 were not expected to have AD. Plus sign (+) in the column on clinical diagnosis indicates additional clinical diagnoses are supported. Bold indicates significance differences from the pure AD cases (Student t-Test, p < 0.01)
From: The neuropathological diagnosis of Alzheimer’s disease
Clinical Dx | Cases (n) | Age (yr) | Brain (g) | Braak | Thal |
|---|---|---|---|---|---|
AD | 109 | 77.3 ± 11.2 | 1061 ± 163 | 5.5 ± 0.7 | 4.7 ± 0.7 |
AD+ | 35 | 73.0 ± 8.5 | 1069 ± 138 | 5.6 ± 0.6 | 4.8 ± 0.5 |
LBD | 16 | 80.9 ± 9.8 | 1073 ± 158 | 5.3 ± 0.6 | 4.5 ± 0.8 |
CBS | 12 | 71.3 ± 7.4 | 1008 ± 169 | 5.9 ± 0.3 | 5.0 ± 0.0 |
FTD | 10 | 66.4 ± 8.9 | 1103 ± 128 | 5.5 ± 1.1 | 4.9 ± 0.4 |
Aphasia | 6 | 72.2 ± 7.1 | 940 ± 109 | 5.9 ± 0.2 | 4.8 ± 0.4 |
Other | 21 | 78.2 ± 10.3 | 1132 ± 155 | 5.4 ± 0.8 | 5.0 ± 0.0 |
MCI | 11 | 87.7 ± 6.9 | 1162 ± 136 | 4.9 ± 0.6 | 5.0 ± 0.0 |
Normal | 7 | 85.9 ± 6.6 | 1251 ± 120 | 4.7 ± 0.8 | 3.0 ± 0.0 |