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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

Fig. 3

Microglial APOE expression in APP/PS1/EKI mice. a Brain sections from APP/PS1/E4F mice were co-stained for nuclei (DAPI), apoE, and IBA1. Multiple foci of apoE/ IBA1 co-localization can be seen (arrows). Scale bar = 20 μm b Brain sections from APP/PS1/E4F mice were co-stained with DAPI, apoE, Aβ, and IBA1. ApoE is co-localized with IBA1 (arrowhead). Scale bar = 25 μm. Images are representative of at least 3 random cortical areas from 3 biological replicates. There were no appreciable qualitative differences between APP/PS1/E2F, APP/PS1/E3F, and APP/PS1/E4F samples

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