Control subjects (70s cohort) | Control subjects (80s cohort) | PD subjects (70s cohort) | PD subjects (80s cohort) | |
---|---|---|---|---|
Cohort size | 10 | 10 | 10 | 8 |
Female (%) | 20.0 | 50.0 | 10.0 | 37.5 |
Male (%) | 80.0 | 50.0 | 90.0 | 62.5 |
Age (years) | 71.2 ± 2.9 | 81.6 ± 4.8 | 71.0 ± 3.3 | 81.9 ± 3.9 |
PMI (hours) | 23.0 ± 4.6 | 22.7 ± 6.5 | 16.3 ± 6.4 | 17.1 ± 6.0 |
Disease duration (years) | N/A | N/A | 15.3 ± 8.2a | 17.4 ± 8.4a |
α-synuclein Braak score | N/A | N/A | Score 4: n = 5 Score 5: n = 5 | Score 1: n = 1 Score 3: n = 1 Score 4: n = 3 Score 5: n = 3 |
Tau Braak score | N/A | N/A | Score 1 n = 2 Score 2: n = 5 Score 3: n = 3 | Score 1 n = 2 Score 2: n = 5 Score 3: n = 1 |
Neuronal loss in SN | Score 0: n = 10 | Score 0: n = 8 Score 0.5: n = 2 | Score 2: n = 1 Score 3: n = 9 | Score 1: n = 1 Score 2.5: n = 1 Score 3: n = 6 |