| | Control subjects | PD subjects |
|---|
Cohort size | 5 | 20 |
Female (%) | 20 | 20 |
Male (%) | 80 | 80 |
Age (years) | 83.4 ± 9.5 | 77.6 ± 6.9 |
PMI (hours) | 15.4 ± 6.9 | 15.9 ± 5.2 |
Disease duration (years) | N/A | 13.5 ± 7.4 |
α-synuclein Braak score | N/A | Score 5: n = 5 Score 6: n = 15 |
Tau Braak score | N/A | Score 1 n = 8 Score 2: n = 11 Score 3: n = 1 |
- PMI post-mortem interval. Data summarised as mean ± SD. α-synuclein Braak score (ranging from 1 to 6) based on Alafuzoff et al., 2009, Acta Neuropathologica. Tau pathology Braak score (ranging from 1 to 6) based on Alafuzoff et al., 2008, Brain Pathology
- 3. Alafuzoff I, Ince PG, Arzberger T, Al-Sarraj S, Bell J, Bodi I, et al. Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium. Acta Neuropathol. 2009;117 (6):635–52
- 4. Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H, et al. Staging of neurofibrillary pathology in Alzheimer’s disease: a study of the BrainNet Europe Consortium. Brain Pathol. 2008;18 (4):484–96
