Cell biological processes impacted by LRRK2. As outlined in the main text, LRRK2 has been implicated in regulating processes at membranous organelles and microtubule-based structures, which are shown in the Figure, as are certain LRRK2-mediated signalling pathways that are likely to be involved. Although not mentioned in the main text, the nucleus is included as the subsequent organellar target of transcription factors affected by LRRK2 signalling. The direct interactions between LRRK2 and Rab29, and LRRK2 and microtubules, are depicted with dashed double-headed arrows. Regulatory mechanisms that are clearly inhibitory to the target are depicted with a round-headed arrow; all other relationships (whether activatory, too complex to categorise as inhibitory or activatory, or as yet undefined) are depicted with conventional arrows.