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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury

Fig. 6

Activation of the DLK-JNK axis in the retinas of IA-injured mice. a, c, e. These horizontal retinal sections were processed for DLK immunohistochemistry and demonstrate the induction of DLK immunoreactivity in cell bodies (asterisks) in the ganglion cell layer and in axons in the nerve fiber layer (arrows) 1 and 3 days post-injury. There is very little immunoreactivity in sham retinas (a). b, d, f. These sections were immunostained for p-JUN and show the presence of many p-JUN (+) nuclei in the ganglion cell layer 1 and 3 days post-injury. Sham-injured retinas (b) are negative. Scale bars: a-f, 50 μm

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