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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

Fig. 5

Overlaps between AMP-AD and key mouse modules: a Overlap between AMP-AD microglia modules in Consensus Cluster B and Apoe−/−-driven ivory module (shown in blue). We identified 22 genes which were present in all AMP-AD microglia modules in Consensus Cluster B and the mouse ivory module (red vertical bar). b Overlap between AMP-AD neuronal modules in Consensus Cluster C and Clu−/− driven brown module (shown in blue). We identified 122 genes which were present in all AMP-AD neuronal modules in Consensus Cluster C and mouse brown module (red vertical bar)

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