Fig. 6

Quantification of total RAD52 in human brain samples. a) Western blot quantification of total RAD52 from unaffected controls (CTL), C9ORF72-related ALS (C9ALS) and sporadic ALS (sALS) in three different brain regions: Occipital cortex (OC) Cerebellum (CB) and Motor cortex (M1). Comparisons between diagnosis groups were performed by mixed effect analyses utilizing data from all three brain regions and accounting for both the between-region differences and within-person correlation; n = 6 per diagnosis group, 3 measurements per person, one from each region. b) Representative western for total RAD52 and beta-actin