Table 2 Fungal involvement in AD
From: Microbial involvement in Alzheimer disease development and progression
Finding | Supported by | Model |
|---|---|---|
Fungal structures in AD brain colocalizes with Aβ plaques | 118, 119 | |
Chitin structures in AD brain | 121, 122 | Human brain tissue |
Fungi in CSF | 123, 124 | Human CSF |
Aβ as an antifungal | 20 | Human brain tissue, in vitro |
Bloodborne Candida can cross BBB | 120 | C57Bl/6, APP−/−, 5xFAD |