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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

Fig. 1

Human and mouse aSyn have seven sequence mismatches. a Sequence alignment of human and mouse aSyn variants showing mismatches at positions 53, 87, 100, 103, 107, 121, and 122. Also highlighted are the positions of familial PD substitutions and known serine and C-terminal tyrosine phosphorylation sites. b Schematic representation of human, mouse, and chimeric aSyn variants examined in this study

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